New method tracks gene expression in single cells over space and time
TEMPOmap can follow thousands of newly made RNA molecules within a cell simultaneously, revealing new insight into how genes are controlled.
This work was funded in part by the Searle Scholars Program, the Thomas D. and Virginia W. Cabot Professorship, the Edward Scolnick Professorship, the Ono Pharma Breakthrough Science Initiative Award, the Merkin Institute Fellows Program at the Broad Institute of MIT and Harvard, and the National Institutes of Health DP2 New Innovator Award.
Ren J, Zhou H, Zeng H, et al. Spatiotemporally resolved transcriptomics reveals subcellular RNA kinetic landscape. Nature Methods. Online Apr. 10, 2023.