Low oxygen levels restore balance and coordination in a mouse model of a movement disorder
New study suggests that treatments that mimic the effects of a low-oxygen environment could one day help reverse Friedreich’s ataxia.
This work was supported in part by the Friedreich’s Ataxia Research Alliance, Marriott Family Foundation, and the National Institutes of Health.
Ast T et al. Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreich’s ataxia. Human Molecular Genetics. Online June 1, 2023. DOI:10.1093/hmg/ddad091.
Rogers RS et al. Hypoxia extends lifespan and neurological function in a mouse model of aging. PLOS Biology. Online May 23, 2023. DOI:10.1371/journal.pbio.3002117.