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News-in-brief / 01.11.16

Team builds hallmark gene set collection from Molecular Signatures Database

By Broad Communications

A team led by Pablo Tamayo and Jill Mesirov of the Broad Institute and University of California, San Diego, and Broad bioinformatician Arthur Liberzon, has generated “hallmark” gene sets from the Molecular Signatures Database (MSigDB), one of the most comprehensive and widely used databases for gene set enrichment analysis. Through both automated and manual approaches, the team curated a refined collection of MSigDB gene sets that reduce redundancy and produce more robust analyses. Their paper is published in Cell Systems.