Archived version MitoCarta1.0: An Inventory of Mammalian Mitochondrial Genes

MitoCarta1.0 is an inventory of 1098 mouse genes encoding proteins with strong support of mitochondrial localization. To generate this inventory, we performed mass spectrometry of mitochondria isolated from fourteen tissues, assessed protein localization through large-scale GFP tagging/microscopy, and integrated these results with six other genome-scale datasets of mitochondrial localization, using a Bayesian approach. We also provide the inventory of 1013 human HomoloGene homologs to the mouse MitoCarta collection.

Citation:

Pagliarini, D.J., Calvo, S.E., Chang, B., Sheth, S.A., Vafai, S.B., Ong, S.E., Walford, G.A., Sugiana, C., Boneh, A., Chen, W.K., et al. (2008). A mitochondrial protein compendium elucidates complex I disease biology. Cell 134, 112-123. [Pubmed: 18614015]

Note MitoCarta2.0 now available!

View MitoCarta1.0 datasets

	Mouse MitoCarta	1098 MitoCarta genes: evidence of mitochondrial protein localization and protein distribution across 14 tissues
	Human MitoCarta	1013 MitoCarta genes: evidence of mitochondrial protein localization and protein distribution across 14 tissues
	GFP localization	Images of 131 protein with mitochondrial localzation assessed by GFP tagging and microscopy

Download MitoCarta1.0 datasets

	Mouse.MitoCarta.xls	Excel database containing detailed information on the 1098 mitochondrial mouse genes, as well as integrated scores of mitochondrial localization for all ~23,000 mouse genes
	Human.MitoCarta.xls	Excel database containing detailed information on the 1013 mitochondrial human genes, as well as integrated scores of mitochondrial localization for all ~17,000 human genes with well-defined mouse homologs from HomoloGene
	MouseMitoCartaAll.sql Mouse.MitoCarta.txt	MySQL database containing detailed information on the 1098 mitochondrial mouse genes, as well as integrated scores of mitochondrial localization for all ~23,000 mouse genes
	HumanMitoCartaAll.sql Human.MitoCarta.txt	MySQL database containing detailed information on the 1013 mitochondrial human genes, as well as integrated scores of mitochondrial localization for all ~17,000 human genes with well-defined mouse homologs from HomoloGene
	Mouse.MitoCarta.bed	BED file of mouse MitoCarta genes within UCSC mouse assembly Feb 2006 (mm8). Use UCSC's Add Custom Tracks to add URL http://www.broad.mit.edu/publications/MitoCarta/Mouse.MitoCarta.bed
	Human.MitoCarta.bed	BED file of human MitoCarta genes within UCSC human assembly March 2006 (hg18). Use UCSC's Add Custom Tracks to add URL http://www.broad.mit.edu/publications/MitoCarta/Human.MitoCarta.bed
	Mouse.MitoCarta.fasta	Fasta file of mouse MitoCarta RefSeq protein sequences
	Human.MitoCarta.fasta	Fasta file of human MitoCarta RefSeq protein sequences