The Getz Laboratory specializes in cancer genome analysis which includes two major steps: (i) Characterization – cataloging of all genomic events and the mechanisms that created them during the clonal evolution of the cancer, comparing events at the DNA, RNA and protein levels between tumor and normal samples from an individual patient; and (ii) Interpretation – analysis of the characterization data across a cohort of patients with the aim of identifying the alterations in genes and pathways that cause cancer or increase its risk as well as identifying molecular subtypes of the disease, their markers and relationship to clinical variables.
Director, Cancer Genome Computational Analysis, Broad Institute
Institute Member, Broad Institute
Director, Bioinformatics Program, Massachusetts General Hospital Cancer Center and Department of Pathology
Associate Professor of Pathology, Harvard Medical School
Paul C. Zamecnik Chair in Oncology, MGH Cancer Center