Bacterial Genomics Group people

Ashlee M. Earl
Senior Group Leader, Bacterial Genomics
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Abigail Manson
Group Leader, Bacterial Computational Genomics

 

 

 

Colin Worby

Colin Worby
Computational Biologist
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Alexandra Grote
Postdoctoral Associate

Alex is a molecular biologist seeking to incorporate computational biology into the study of infectious disease and host-pathogen interactions. She is currently using comparative genomics and transcriptomics to identify bacterial and host factors that govern Salmonella persistence. Before joining the Broad Institute, she received her PhD in biology from New York University where she studied the endosymbiotic relationship that parasitic nematodes have with the bacteria Wolbachia.

Tim Straub
Tim Straub
Associate Computational Biologist

Tim Straub joined the Broad Institute in 2015 where he works mainly in the realm of microbial genomics and evolution, with a strong focus on bacteria. He splits his time between the bacterial and the malarial genomics groups at the GCID, assisting on multiple fronts studying the genomics of infectious diseases and collaborating with other research groups across the Harvard and MIT community. Current projects include the EnteroGenome project (collaborating with the Gilmore lab) and the genomics of Wolbachia parasite in Anopheles gambiae mosquitoes (Catteruccia lab). Before joining the Broad, he received his Bachelor's of Science from Tufts University as well as his Master's of Science from Dartmouth College.

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Ryan Bronson
Associate Computational biologist

Ryan is an associate computational biologist interested in the evolution of drug resistance and microbial population genetics. She is currently working on comparative genomics projects to examine determinants of drug resistance in bacteria. Before joining the group, Ryan received a B.S. in Applied Mathematics-Biology from Brown University.

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Lucas Van Dijk
Associate Computational biologist

 

 

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Aysun Urhan
Visiting graduate student

Aysun is a visiting PhD student, currently working on the EnteroGenome project. She is doing her PhD thesis at Delft University of Technology in Thomas Abeel's group, exploring antimicrobial resistance in pathogenic bacteria. She is interested in comparative genomics using pan-genome graphs. Before joining the group, Aysun has received a B.Sc. and M.Sc. in chemical engineering at Bogazici University in Istanbul.

 

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Andrew Van Camp
Visiting student

Andrew is a visiting undergraduate student interested in microbial ecology and the evolution of antibiotic resistance. He is currently working on the EnteroGenome project in collaboration with the Gilmore Lab. He studies Applied Math at Harvard.

 

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Sophie Green
Visiting student
Sophia Green is a visiting student who will be attending MIT as a freshman in the fall of 2021. She is passionate about programming and its application in a variety of fields, especially life sciences. Currently, she is working on creating truth data sets for a bacterial genomics project.

 

 

Bruce Walker

Bruce Walker
Visiting Scientist
Thomas Abeel
Visiting Scientist

Thomas Abeel is an Associate Professor at the Department of Intelligent Systems of the Faculty of Electrical Engineering, Mathematics and Computer Science at the TU Delft. He is working with the Broad Bacterial Genomics group on several projects, including methods development projects. Read more

Keira Cohen
Visiting Scientist

 

Sr. Research Scientist
 
 

 

Previous Group Members

Wen-Chi Chou
Postdoctoral Associate
Senior Computational Scientist

Gustavo's research in the bacterial genomics group involved the identification of the genetic causes of infectivity, pathogenicity and resistance to drugs and antibiotics in human and livestock pathogens. He used genotype-phenotype association methods based on gene content difference, single nucleotide polymorphisms and genome structural variants to accomplish that. Gustavo has a Ph.D. in Bioinformatics from the Universidade Federal de Minas Gerais (Brazil) and held positions at The Institute for Genomic Research (TIGR, currently JCVI) and the Institute for Genome Sciences (IGS, University of Maryland School of Medicine), before working at the Broad institute from 2011-2017.  

Senior Computational Biologist

Chris is interested in the genetic basis of pathogenicity and drug resistance in bacteria and fungi, and exploring phylogenetic and other evolutionary methods to uncover these relationships. His recent work focused on the evolution of drug resistance in Mycobacterium tuberculosis and virulence in Cryptococcus neoformans. Chris has a Ph.D. in Entomology from the University of Maryland, College Park and held postdoctoral positions at The Institute for Genomic Research (TIGR, currently JCVI) and the University of Rochester, before working at the Broad institute from 2010-2017.  

Alejandro Pironti
Postdoctoral Associate

Alejandro is interested in precision medicine for infectious disease. He analyses bacterial genomes in order to identify and track the genetic elements that make bacteria resistant or susceptible to antibiotics. Alejandro's current projects focus on the spread of carbapenem resistance in nosocomial Enterobacteriaceae and on the determinants of synergistic effects in antibiotic combinations.  Before joining the Broad Institute, Alejandro performed research in the field of antiretroviral combination therapy. He earned his Ph.D. in Computational Biology at the Max Planck Institute for Informatics (Germany), before working at the Broad Institute from 2016-2021.

Rauf Salamzade
Associate Computational Biologist