The Wagner Group conducts research in the following areas:
- Identifying small-molecule inducers of human beta-cell proliferation
- Chemical approaches to beta-cell transdifferentiation from alpha cells and from exocrine cells
- Suppression of cytokine-induced beta-cell apoptosis
- Nutrient profiling
- Profiling small-molecule sensitivity across a panel of pancreatic cell lines
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Role of reactive oxygen species in type 1 diabetes and its modulation by small molecules
