Computational Research and Development

Welcome to the Computational Research and Development Group (CRD) homepage. We are part of the Genome Sequencing and Analysis Program at the Broad Institute. This site presents tools we have developed for genome assembly and variant detection. We thank the National Human Genome Research Institute and National Institute of Allergy and Infectious Diseases for supporting the development of these tools.

Our goal is to produce high-quality draft sequences and variant calls at low cost. To do this, we look for the optimal deployment of cutting-edge sequencing technologies and assembly and variant calling algorithms.

Genome assembly and variant calling

Genome assembly

Genome variant detection