Breadcrumb Home CMS Results The following tables summarize our results from a genome-wide CMS analysis of the 1000 Genomes pilot release data. CMS scores Genome-wide CMS scores in the YRI, CEU, and JPT+CHB Localized CMS regions: List of localized regions CMS scores for localized regions Genome-wide scores as a UCSC Genome Browser track (these files can be uploaded as a custom track and viewed using the UCSC Genome Browser) Functional annotation These tables contain functional annotation and enrichment analysis of the selected regions. Tables from Publication Regions identified by genome-wide CMS xlsx Localized CMS regions xlsx Enrichment of functional variants xlsx Enrichment of gene pathways xlsx Candidate selective regions that overlap lincRNAs xlsx Characterization of high-scoring non-synonymous SNPs xlsx Candidate selective regions that overlap eQTLs xlsx CMS high-scoring SNPs in active enhancers or promoters xlsx Trait-associated CMS high-scoring SNPs xlsx Additional Tables Structural variants in selected regions xlsx Enrichment analysis was done using INRICH[1] and a set of manually curated lists as reference functional pathways. References Lee PH, O'Dushlaine C, Thomas B, Purcell SM. INRICH: interval-based enrichment analysis for genome-wide association studies. Bioinformatics. 2012 Jul 1;28(13):1797-9. Epub 2012 Apr 17. PubMed PMID: 22513993. Composite of Multiple Signals Overview Results CMS Viewer Code Publications Contact Latest news News 02.05.2025 Mutations in two gene pairs point to a promising drug target in 5 percent of adult cancers News 01.27.2025 A genome-wide atlas of cell morphology reveals gene functions News 01.16.2025 Study finds surprising way that genetic mutation causes Huntington’s disease, transforming understanding of the disorder News 01.14.2025 Gene editing extends lifespan in mouse model of prion disease All news
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