The following tables summarize our results from a genome-wide CMS analysis of the 1000 Genomes pilot release data.
Localized CMS regions:
Genome-wide scores as a UCSC Genome Browser track (these files can be uploaded as a custom track and viewed using the UCSC Genome Browser)
These tables contain functional annotation and enrichment analysis of the selected regions.
|Tables from Publication|
|Regions identified by genome-wide CMS||xlsx|
|Localized CMS regions||xlsx|
|Enrichment of functional variants||xlsx|
|Enrichment of gene pathways||xlsx|
|Candidate selective regions that overlap lincRNAs||xlsx|
|Characterization of high-scoring non-synonymous SNPs||xlsx|
|Candidate selective regions that overlap eQTLs||xlsx|
|CMS high-scoring SNPs in active enhancers or promoters||xlsx|
|Trait-associated CMS high-scoring SNPs||xlsx|
|Structural variants in selected regions||xlsx|
Enrichment analysis was done using INRICH and a set of manually curated lists as reference functional pathways.
- Lee PH, O'Dushlaine C, Thomas B, Purcell SM. INRICH: interval-based enrichment analysis for genome-wide association studies. Bioinformatics. 2012 Jul 1;28(13):1797-9. Epub 2012 Apr 17. PubMed PMID: 22513993.