Selected Publications

Wang X, He L, Goggin S, Saadat, A, Wang L, Claussnitzer M*, Kellis M* (*co-senior and co-corresponding). High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human. Nature Communications. 2018 Dec 19; 9(1):5380.

Quon G, Feizi S, Marbach D, Claussnitzer M, Kellis M. Predicting trait regulators by identifying co-localization of DNA binding and GWAS variants in regulatory regions. bioRxiv 467852 [Preprint]. November 11, 2018.

eGTEx Project. Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease. Nat Genet. 2017 Dec;49(12):1664-1670.

Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Johanna J, Wassel C, Register TC, Oei L, Alonso Lopez N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L, Terry G, Cox AJ, Allison MA, Criqui MH, Bowden D, Ikram MA, Mellström D, Karlsson MK, Carr J, Budoff M, Phillips C, Cupples LA, Chou WC, Myers RH, Ralston SH, Gautvik KM, Cawthon PM, Cummings S, Karasik D, Rivadeneira F, Gudnason V, Orwoll ES, Harris TB, Ohlsson C, Kiel DP, Hsu YH. Novel Genetic Variants are Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SCL1A3 and EPHB2. J Bone Miner Res. 2016 Aug 1.

Claussnitzer M, Dankel SN, Quon G, Kim KH, Meuleman W, Haugen C, Glunk V, Puviindran V, Abdennur N, Liu J, Svensson P, Hsu YH, Mellgren G, Hui CC, Hauner H, Kellis M. FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. The New England Journal of Medicine. 2015. Sep 3;373(10):895-907.

Claussnitzer M, Hui CC, Kellis M. FTO Obesity Variant and Adipocyte Browning in Humans. The New England Journal of Medicine. 2016 Jan 14;374(2):192-3.

Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M. Integrative analysis of 111 reference human epigenomes. Roadmap Epigenomics Consortium. Nature. 2015.

Dankel SN, Svärd J, Matthä S, Claussnitzer M, Klöting N, Glunk V, Fandalyuk Z, Grytten E, Solsvik MH, Nielsen HJ, Busch C, Hauner H, Blüher M, Skurk T, Sagen JV, Mellgren G. COL6A3 Expression in adipocytes associates with insulin resistance and depends on PPARγ and adipocyte size. Obesity. 2014

Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess L, Müller-Nurasyid M, Skurk T, Bretschneider N, Schroeder T, Skurk T, Horsthemke B, DIAGRAM+ Consortium, Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck S, Blüher, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. Cell. 2014; 156(1-2):343-58.

Claussnitzer M, Skurk T, Hauner H, Daniel H, Rist MJ. Effect of flavonoids on basal and insulin-stimulated-deoxyglucose uptake in adipocytes. Mol Nutr Food Res. 2011 Suppl 1:S26-34.