MIT Chemistry and the Broad Institute host monthly seminars in chemical biology with the intent to hear from the thought-leaders and bring together chemical biologists from both academia and industry in the Boston/Cambridge area.
2025-2026 Speakers
| 05/18/2026 | TBD | Michelle Chang Princeton University |
| 04/27/2026 | TBD | Samira Musah Duke University |
| 04/13/2026 | TBD | Deb Hung Broad Institute of MIT and Harvard |
| 02/23/2026 | The Druggable Transcriptome Project: From Chemical Probes to Lead Precision Medicines | Matt Disney Scripps Research Institute |
| 11/03/2025 | Covalent drug discovery: from serendipity to clinical trials | Jack Taunton UCSF |
2024-2025 Speakers
| 05/12/2025 | Structural plasticity in alphavirus interactions with cellular receptors [recording] |
Jonathan Abraham Harvard Medical School |
| 04/28/2025 | Directed and Random Walks in Chemical Space [recording] |
Brian Shoichet UCSF |
| 03/03/2025 | Molecular Glues - from Protein Degradation to Transcription Factor Reprogramming [recording] |
Nathanael Gray Stanford University |
| 02/24/2025 | Replicating RNA with RNA [recording] |
Phil Holliger MRC Laboratory of Molecular Biology |
| 02/10/2025 | Genome Mining for New Natural Products [recording] |
Wilfred van der Donk University of Illinois Urbana-Champaign |
| 11/04/2024 | Eavesdropping on the Gut Microbiome [recording] |
Jim Wells UCSF |
| 10/07/2024 | Disorder Rules: Transcription Factors [recording] |
H. Jane Dyson Scripps Research Institute |
| 09/23/2024 | Eavesdropping on the Gut Microbiome | Jon Clardy Harvard Medical School |
2023-2024 Speakers
| 05/20/2024 | Decoding Glycosaminoglycans and Their Roles in Neuroplasticity | Linda Hsieh-Wilson Caltech |
| 04/29/2024 | GPCR to channel communication in a membrane signaling pathway | Rod MacKinnon Rockefeller University |
| 04/22/2024 | Overcoming the Undruggable Nature of the Most Common Human Oncogene, K-Ras | Kevan Shokat UCSF |
| 04/08/2024 | Molecular origami: Understanding how proteins fold and misfold in living cells | Judith Frydman Stanford University |
| 03/25/2024 | Deciphering the mechanisms of lipid trafficking in bacteria | Laura Dassama Stanford University |
| 02/05/2024 | Recording the Physiological History of Cells with Chemical Labeling | Kai Johnsson Max Planck Institute |
| 01/29/2024 | Activity-based proteomics – protein and ligand discovery on a global scale | Ben Cravatt Scripps Research Institute |
| 01/08/2024 | Two medicines that have saved at least 100 million lives | Ed Scolnick Broad Institute |
| 11/06/2023 | Biological and technological frontiers for single-cell proteomics [recording] |
Nikolai Slavov Northeastern University |
| 10/02/2023 | Making it stick: How to engineer selective covalent ligands for diverse applications in biology [recording] |
Matt Bogyo Stanford University |
| 05/08/2023 | Chemical Biology of extracellular cGAMP signaling in health and disease | Lingyin Li Stanford University |
| 04/24/2023 | Multum in parvo—The mechanism of a protein antibiotic [recording] |
Bill Clemons California Institute of Technology |
| 04/03/2023 | A radical solution for C(sp3)—C(sp3) bond formation during the biosynthesis of macrocyclic membrane lipids [recording] |
Squire Booker Pennsylvania State University |
| 03/06/2023 | Reprogramming the Genetic Code | Jason Chin MRC Laboratory of Molecular Biology |
| 02/27/2023 | The development of chemical probes of histone “reader” subunits of chromatin remodeling complexes | Emily Dykhuizen Purdue University |
| 02/06/2023 | Pharmacological Adaptation of Proteostasis to Ameliorate Aging-associated Degenerative Diseases [recording] |
Jeffrey Kelly Scripps Research Institute |
| 01/30/2023 | RNA modification in gene expression regulation [recording] |
Chuan He The University of Chicago; HHMI |
2019-2022 Speakers
| 11/21/2022 | Biomolecular condensates: new insights into regulation and dysregulation of cellular compartments [recording] |
Richard Young Whitehead Institute; MIT |
| 10/24/2022 | Base Editing and Prime Editing: Precise Chemistry on the Genome without Double—Strand DNA Breaks [recording] |
David Liu Broad Institute; Harvard University; HHMI |
| 09/19/2022 | Exploring protein-glycan interactions in immunity [recording] |
Laura Kiessling MIT |
| 02/24/2020 | Lipid and light-driven tools for cell biology | Carsten Schultz Oregon Health; Science University |
| 12/09/2019 | Reimagining Druggability using Chemoproteomic Platforms | Daniel K. Nomura University of California, Berkeley |
| 11/04/2019 | Deciphering the Human Microbiota with Chemistry | Emily Balskus Harvard University |
| 10/15/2019 | Pseudo Natural Products - Chemical Evolution of Natural Product Structure | Herbert Waldmann Max Planck Institute |
| 09/11/2019 | Listening to Probes: Individuals and Populations [recording] |
Stuart Schreiber Broad Institute |



