CDoT is disease area agnostic, guided by the highest quality science-driven therapeutic hypotheses from the Broad PI community. Thanks to CDoT’s position within the Broad Institute, the rationale for projects accepted into the CDoT portfolio draws from a deep understanding of the genetics of specific human disease. 

CDoT is currently working in the disease areas of oncology, cardiovascular, immunoregulation, psychiatry, and kidney disease. CDoT is involved in projects that span all stages of the drug discovery process.