Cell Circuits and Complex Tissues
The vast number and variety of activities our cells need to undertake to maintain health rely on finely tuned circuits involving multiple genes and molecules. Deciphering the genetic and molecular basis of circuits inside cells is critical to understand the impact of genetic variations on these circuits. How do molecules within cells function to perform their functions? How do malfunctions in genes and cells cause or exacerbate disease? Our goal is to develop a comprehensive and quantitative analysis of cell circuits that will enable researchers to better understand disease and develop effective new treatments.