2013 Broad Summer Scholars

Worked on developing a platform for the analysis of high-throughput data concerning functional cancer genomics.

Evaluated controls for a technique called chromatin immunoprecipitation (ChIP), which is used to study how proteins and DNA interact in a cell.

Worked with a protein implicated in pancreatic cancer called Retinoblastoma-binding Protein 9 (RBBP9).

Explored factors that allow tuberculosis to survive in its latent state, as well as the prospect of targeting those factors.

Synthesized chemical analogs of a lead compound to identify potential drug candidates to cure malaria.

Focused on microfluidics—the science of manipulating fluid flow on a sub-millimeter scale.

Synthesized and tested Diversity-Oriented Synthesis compounds (DOS) to see if they could inhibit an enzyme that malaria needs to survive.

Researched a gene called TERT, which signals the production of telomerase—an enzyme that prolongs cell life and is present in 85% of cancerous cells. Joan

Research project involved the screening of a Diversity Oriented Synthesis (DOS) compound and its 70 analogs against lung carcinoma cell lines.

Worked on characterizing novel fluorescent dyes for cell cycle analysis.

Worked on the synthesis and identification of cysteine-active small molecules.

Modeled cancer cell evolution using a programming language called R.

Used the Gene Set Enrichment Analysis Program to construct gene sets.

Researched sites of Allele-specific gene expression.

Worked on a genome wide association (GWAS) of golden retrievers with several subsets of sarcoma, a kind of cancer.