As part of a nationwide collaboration, Broad Clinical Labs researchers have optimized 10 polygenic scores for use in clinical research as part of a study on how to implement genetic risk prediction for patients.
By using genetic data on multiple traits from people of non-European ancestry, scientists have improved the accuracy of polygenic scores in predicting disease risk for all.
The largest psychiatric genetics study ever done in Africa is increasing the diversity of data on mental illness, training a new generation of geneticists, and chipping away at the genetic underpinnings of schizophrenia and bipolar disorder.
In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk.