News 04.29.2021 Large collaboration creates cell atlas of COVID-19 pathology Single-cell analysis of autopsy samples from COVID-19 patients shows how the lungs repeatedly tried, and failed, to repair themselves. Klarman Cell Observatory Regev Lab Coronavirus Single cell genomics Single Cell Read more
News 03.11.2021 A better understanding of the immune system in kidney cancer Two research papers highlight single-cell dissection of kidney tumors to identify new immunotherapy treatments and targets Cancer Program Cancer Single cell genomics Single Cell Read more
News 03.08.2021 New single-cell technology points to mechanism of cancer immunotherapy resistance Researchers used Perturb-CITE-seq to identify a protein involved in resistance to immune checkpoint inhibitors. Klarman Cell Observatory Regev Lab Cancer Gene-Expression Profiling Single Cell Read more
Blog 02.18.2021 #WhyIScience Q&A: How a physician-scientist’s clinical experience shapes his infectious disease research Research fellow Pierre Ankomah discusses what brought him to the United States and the mentors who helped him along the way. Infectious Disease and Microbiome Single cell genomics Gene-Expression Profiling Single Cell Read more
News 12.16.2020 Cellular connections found between nervous and immune systems Pain-sensing neurons link to lymph nodes and potentially regulate their activity. Single cell genomics Single Cell Read more
News 09.03.2020 A single-cell atlas of nerve cells in the gut reveals web of connections New techniques enable researchers to analyze rare cells in the gastrointestinal tract and find links to the immune system and various disorders Klarman Cell Observatory Metabolism Program Regev Lab Xavier Lab Inflammatory bowel disease Single Cell News and Media Read more
News 08.27.2020 Single-cell profiling of multiple cell lines can reveal cancer vulnerabilities and drug mechanisms New method analyzes dozens of cancer cell lines at once for their responses to a drug or gene disruption Cell-Line Profiling Single Cell Read more
News 06.04.2020 Single-cell map of the heart reveals wide cellular diversity The largest single-nucleus survey of the human heart to date uncovers several new cell types and a variety of gene expression patterns. Precision Cardiology Laboratory Heart Disease Single cell genomics Single Cell Read more
News 06.03.2020 How DNA crossovers can drive both healthy and abnormal sperm formation A single biological process may regulate key aspects of how parents' DNA recombines in sperm development Single cell genomics Single Cell Read more
Blog 05.21.2020 Researchers study single cells to ask why children generally fare better against COVID-19 In #WhyIScience Q&A, medical engineer Alex K. Shalek and biologist Jose Ordovas-Montanes talk about their work on pediatric COVID-19 patient samples and how they quickly pivoted their research to respond to the pandemic. HCA Klarman Cell Observatory Coronavirus Human Cell Atlas: International collaboration Human Cell Atlas: Reading biology Single cell genomics Single Cell Read more