Regev Lab

In defining the cellular context of diffuse midline gliomas, researchers find the cells fueling their growth and suggest a potential approach to treating them: forcing their cells to be more mature.

Naomi Habib and Yinqing Li, researchers from the labs of Broad core institute members Aviv Regev and Feng Zhang, report on a new contribution to the single-cell analysis toolkit. Their method combines the sequencing of RNA from isolated nuclei (sNuc-Seq), and tagging of regenerating cells (Div-Seq), to enable the study of previously intractable and rare cell types in the brain.