By using genetic data on multiple traits from people of non-European ancestry, scientists have improved the accuracy of polygenic scores in predicting disease risk for all.
In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk.
Through “polygenic risk scoring,” researchers can identify people at high risk for disease, even if they don’t present other warning signs; method shows potential for use in the clinic