Prolonged physical activity in rats results in profound changes to RNA, proteins, and metabolites in nearly all tissues, providing clues to many human health conditions.
A single-cell study of “persister” cells shows how they proliferate under drug treatment and could help scientists develop better therapeutics to prevent cancer recurrence.
Researchers take a broad, multi-faceted look at a large collection of cancer cell lines, creating a new trove of data to explore for drug development opportunities.
Because of their immediacy to cell physiology, metabolites are promising biomarkers for disease, as well as clues to genetic or drug alterations in the cell.