News 06.30.2023 New image-based cellular profiling tool peers deeply into metabolic biology LipocyteProfiler captures disease-relevant phenotypes in an inexpensive microscopy assay Imaging Platform Metabolism Program Connecting variants to functions Cardiovascular disease Diabetes Obesity Heart Disease Image-Based Profiling Read more
News 06.21.2023 Low oxygen levels restore balance and coordination in a mouse model of a movement disorder New study suggests that treatments that mimic the effects of a low-oxygen environment could one day help reverse Friedreich’s ataxia. Metabolism Program Rare Disease Read more
News 05.25.2023 Study finds how a genetic variant raises diabetes risk through an unexpected mechanism The variant contributes to a unique form of diabetes by reducing fat cells' ability to store fat and respond to insulin Metabolism Program Diabetes Connecting variants to functions Read more
News 05.17.2023 Cells can use uridine, a component of RNA, as a source of energy Researchers have discovered a new biochemical pathway in cells that could contribute to the immune response as well as some cancers and metabolic disorders. Metabolism Program Obesity Read more
News 04.06.2023 Targeting a unique metabolic pathway might starve pancreatic cancer Researchers discover that pancreatic ductal adenocarcinoma depends on a unique metabolic pathway to make compounds necessary for its growth Metabolism Program Metabolomics Platform Cancer Read more
News 09.19.2022 Broad Discovery Center in Cambridge opens to the public this October Visitors are invited to explore galleries highlighting key discoveries and transformative insights in biomedicine. Gerstner Center for Cancer Diagnostics NeuroGap Precision Cardiology Laboratory Cancer Program Chemical Biology and Therapeutics Science Program Genetic Perturbation Program Imaging Platform Medical and Population Genetics Program Metabolism Program Infectious Disease and Microbiome Program ... Read more
News 09.23.2021 HHMI honors five Broad researchers The scientists will receive flexible, long-term funding to pursue cutting-edge research projects. Chemical Biology and Therapeutics Science Program Metabolism Program Read more
News 03.15.2021 SARS-CoV-2 hijacks two key metabolic pathways to rapidly replicate in host cells Study suggests blocking folate metabolism with oral, prophylactic drugs could reduce viral replication in infected cells Metabolism Program Infectious Disease and Microbiome Program Coronavirus Mass Spectrometry Read more
News 09.03.2020 Broad Institute launches new effort to study rare neuromuscular disorder The Friedreich’s Ataxia Accelerator will apply genomics tools to promote discovery of new treatments Metabolism Program FAA Read more
News 09.03.2020 A single-cell atlas of nerve cells in the gut reveals web of connections New techniques enable researchers to analyze rare cells in the gastrointestinal tract and find links to the immune system and various disorders Klarman Cell Observatory Metabolism Program Regev Lab Xavier Lab Inflammatory bowel disease Single Cell Aviv Regev News and Media Read more