Klarman Cell Observatory

The findings help illuminate key cells and biological pathways involved in the disease, which could help inform the development of future treatments.

Harvard and Broad researchers use miniature 3D models of the human brain to study the biological functions of genetic risk factors

Broad scientists have developed a new approach for studying the functional effects of the millions of mutations associated with cancer and other diseases

Researchers find key biological factors associated with efficacy of the tuberculosis vaccine, and suggest ways to further study and monitor vaccine-induced immunity.

New study hints that colorectal tumors containing these immune hubs might be more likely to respond to existing immunotherapies.

A single-cell study of “persister” cells shows how they proliferate under drug treatment and could help scientists develop better therapeutics to prevent cancer recurrence.

Cells taken from patients at the time of diagnosis who later developed severe COVID-19 show a muted antiviral response, study finds

Harvard and Broad researchers combine single-cell genomic technologies to map the mouse cortex

Single-cell analysis of autopsy samples from COVID-19 patients shows how the lungs repeatedly tried, and failed, to repair themselves.