New map of chronic lymphocytic leukemia could potentially help identify new diagnostic markers, offer more accurate prognoses, and develop novel treatments.
Single-cell RNA sequencing maps immune microenvironment changes that arise before myeloma appears, and reveals opportunities for developing personalized treatments.
The new tool more accurately distinguishes mutations that drive cancer from ones that don’t, and could help focus future research and drug development.
A clinical study comparing liquid and tissue biopsies finds multiple resistance mechanisms in individual patients, which could explain why targeted therapies often fail.
By matching cells' growth trajectories to their genetic features, a team finds CLL cells' arc of growth is written into their genes early in disease development.