DepMap

Large-scale collaboration will leverage each institution’s expertise and infrastructure to advance understanding of the biological basis of pediatric cancers, identify new vulnerabilities of these diseases and accelerate cures globally

Visitors are invited to explore galleries highlighting key discoveries and transformative insights in biomedicine.

A study looking for cancer genetic dependencies suggests that disrupting phosphate regulation in cancer cells could be a therapeutic strategy.

New computational tool uses gene expression data to measure how closely laboratory cancer models compare to real tumors

Genetic screens point to VPS4A and VPS4B as promising cancer drug targets

Cancer cells that have lost a copy of a critical gene may be vulnerable to therapies that knock out the remaining copy

Study will help narrow down the list of targets for the next generation of cancer treatments

Cancer cells that cannot repair a certain form of DNA mutation become strongly dependent on single enzyme to survive, creating a new potential opportunity for drug development.