CRISPR

Inexpensive, sensitive, CRISPR-based tests diagnose two deadly viruses in settings with limited infrastructure

BE-Hive can tell which base editor performs best to repair thousands of disease-causing mutations

Cas9 can cut DNA without any guide RNA and select for cells with inactivated p53.

New CRISPR-based research tool delivers results in an hour in a one-step reaction; Researchers share protocol and kits to advance research and move toward clinical validation.

The diagnostic platform CARMEN combines microfluidics with the CRISPR-based detection technology SHERLOCK, and could one day be used for public health efforts.

A new adenine base editor expands the range of genetic sites that can be edited in human cells, with speed and efficiency far surpassing the original editor.

New CRISPR base editors make fewer off-target edits and can access more locations on the genome than earlier versions.

“Prime editing” combines two key proteins and a new RNA to make targeted insertions, deletions, and all possible single-letter changes in the DNA of human cells

New image-based genetic screening method helps researchers identify key regulators of inflammation.