News 11.07.2022 Scientists unveil the functional landscape of essential genes Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 genes that human cells require to survive Blainey Lab CRISPR Image-Based Profiling Read more
News 09.19.2022 Broad Discovery Center in Cambridge opens to the public this October Visitors are invited to explore galleries highlighting key discoveries and transformative insights in biomedicine. Gerstner Center for Cancer Diagnostics NeuroGap Precision Cardiology Laboratory Cancer Program Chemical Biology and Therapeutics Science ... Read more
News 04.28.2022 Researchers use CRISPR to build melanoma models from scratch using human cells By introducing cancer-causing mutations into healthy skin cells step-by-step, Broad scientists have created models of skin cancer that can reveal the effects of mutations. Regev Lab Cancer CRISPR Aviv Regev News and Media Read more
News 09.09.2021 New programmable gene editing proteins found outside of CRISPR systems RNA-guided enzymes are more diverse and widespread than previously believed Zhang Lab Gene editing CRISPR Feng Zhang News and Media Read more
News 06.02.2021 Genetic base editing treats sickle cell disease in mice Converting a pathogenic hemoglobin gene to a benign variant enables healthy blood cell production in an animal model of sickle cell disease. Genomics Gene editing CRISPR David Liu News and Media Read more
News 01.06.2021 Base editing successfully treats progeria in mice Correcting the mutation that causes progeria with base editing leads to strong symptom reduction and longer lifespan in an animal model Chemical Biology and Therapeutics Science Rare Disease Gene editing CRISPR David Liu ... Read more
News 12.03.2020 Large-scale tool helps reveal function of autism spectrum disorder genes Scientists apply the “Perturb-Seq” method to a living organism for the first time Klarman Cell Observatory Stanley Center for Psychiatric Research Connecting variants to functions Gene editing CRISPR ... Read more
News 11.20.2020 Rapid COVID-19 test delivers accurate results with minimal equipment The experimental CRISPR-based test, with further development, could potentially be used outside of labs. Infectious Disease and Microbiome Coronavirus Infectious Disease and Microbiome SHERLOCK CRISPR ... Read more
News 09.17.2020 Rapid test for COVID-19 shows improved sensitivity A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard COVID-19 diagnostic. Zhang Lab Coronavirus SHERLOCK CRISPR Feng Zhang ... Read more
News 08.26.2020 Rapid diagnostic detects Lassa and Ebola in real-time Inexpensive, sensitive, CRISPR-based tests diagnose two deadly viruses in settings with limited infrastructure Infectious Disease and Microbiome Infectious Disease and Microbiome SHERLOCK CRISPR Pardis Sabeti ... Read more