A study of tumor exomes reconstructs a timeline of mutations for certain cancer types, revealing insight into the order of genetic drivers of the disease.
By integrating clinical, genetic, and other data from patients with lung cancer, researchers identify biological factors that could help predict treatment outcomes.
The new Leiomyosarcoma Project joins an existing effort, Count Me In’s Osteosarcoma Project, to partner with patients and accelerate scientific discovery in rare cancers.
New map of chronic lymphocytic leukemia could potentially help identify new diagnostic markers, offer more accurate prognoses, and develop novel treatments.
Scientists have solved the structure of an important complex of RAS-pathway proteins, explaining how known mutations lead to disease and suggesting potential new binding sites for cancer drugs.