Aviv Regev

By introducing cancer-causing mutations into healthy skin cells step-by-step, Broad scientists have created models of skin cancer that can reveal the effects of mutations.

Using a new mathematical framework, researchers examine signatures of natural selection in the genome, deciphering the evolutionary past and future of noncoding DNA

Broad scientists have developed a new approach for studying the functional effects of the millions of mutations associated with cancer and other diseases

New study hints that colorectal tumors containing these immune hubs might be more likely to respond to existing immunotherapies.

Harvard and Broad researchers combine single-cell genomic technologies to map the mouse cortex

Single-cell analysis of autopsy samples from COVID-19 patients shows how the lungs repeatedly tried, and failed, to repair themselves.

Researchers used Perturb-CITE-seq to identify a protein involved in resistance to immune checkpoint inhibitors.

Study of T cells from glioma tumors identifies a pathway that inhibits immune response

Scientists apply the “Perturb-Seq” method to a living organism for the first time

New techniques enable researchers to analyze rare cells in the gastrointestinal tract and find links to the immune system and various disorders