• White House selects David Altshuler as “Champion of Change”

    Haley Bridger, June 20th, 2013

    Today, the White House will honor David Altshuler, on behalf of the global alliance for sharing genomic and clinical data, as an Open Science Champion of Change. The White House selected Altshuler for his “tremendous work and leadership” as part of this global alliance to develop a common framework for sharing scientific data.

    Read More
  • ATARiS hits the jackpot

    Haley Bridger, May 21st, 2013

    Listening to data isn’t easy. Massive amounts of data are often messy and complicated. But somewhere within the cacophony, information can harmonize and produce the sweet sound of discovery – if you have the right tools with which to hear it.

    Read More
  • HHMI selects four Broad researchers for prestigious honor

    Haley Bridger, May 9th, 2013

    The Howard Hughes Medical Institute (HHMI) announced today that four scientists from the Broad Institute are among the 27 “top biomedical researchers” in the nation who will become HHMI investigators this fall. Selected for their scientific excellence, all of the investigators will receive flexible, financial support over the next five years so that they may move their research forward in creative and new directions. The Broad Institute’s Aviv Regev, Vamsi Mootha, Peter Reddien, and David Reich are among the new group of HHMI investigators.

    Read More
  • A need for speed

    Haley Bridger, May 6th, 2013

    A patient’s genetic sample holds great promise – but to capitalize on it, researchers need to crack open the information within, analyze it, and return the data to doctors in time to influence critical healthcare decisions. Broad Institute researcher Chris Friedrich and his team are challenging themselves to find ways to deliver information faster than ever before, efforts that in the future could help patients.

    Read More
  • "Coelacanth Chat" coming soon

    Haley Bridger, April 23rd, 2013

    Last week, we shared exciting news about the sequencing of the coelacanth genome with you in a Broad press release and video. If you want to learn more about coelacanths, join us online this Thursday, April 24, at 11 a.m. EST.  Watch live as science writer Carl Zimmer and scientists from the team that sequenced this remarkable fish’s genome explore the stories behind the science, discuss the latest discoveries, and answer your questions in a Google Plus Hangout On Air.

    Read More
  • Rewinding the clock with epigenomics

    Haley Bridger, March 28th, 2013

    How does a single cell give rise to a fully formed organism? Insights from induced pluripotent stem (iPS) cells – cells whose developmental clocks have been wound backward to an earlier time – have helped scientists develop a deeper understanding of this process. Since scientists discovered how to create iPS cells seven years ago, researchers have begun to see parallels between the steps required to make iPS cells in the dish and the molecular events that unleash a cancer cell.

    Read More
  • Eric Lander wins Breakthrough Prize in Life Sciences

    Haley Bridger, February 20th, 2013

    Eric Lander, the Broad Institute’s president and founding director, is among 11 recipients of the first Breakthrough Prize in Life Sciences, an award that recognizes excellence in research aimed at curing intractable diseases and extending human life. Founding sponsors of the Breakthrough Prize include Sergey Brin, Anne Wojcicki, Mark Zuckerberg, and Yuri Milner. Art Levinson will serve as the Chairman of the Board of the Foundation administering the prize.

    According to today’s prize announcement, Lander was selected for the discovery of general principles for identifying human disease genes, and enabling their application to medicine through pioneering work to create and analyze genetic, physical and sequence maps of the human genome.

    Read More
  • MuTect: An engine powering cancer genome analysis

    Haley Bridger, February 13th, 2013

    Over the last year, researchers at the Broad and elsewhere have analyzed genes in over 100 samples of breast cancer, identified new pathways in head and neck cancer, uncovered new subtypes of prostate cancer, and revealed significant mutations in dozens of forms of cancer. Behind all of these studies lies a central tool developed by Broad researchers: MuTect. Used to detect point mutations – single “letter” alterations in the genome that may help twist a normal cell into a cancerous one – the MuTect algorithm is one of the engines powering cancer genome analysis.

    Read More
  • Genome engineering gets CRISPR

    Haley Bridger, January 9th, 2013

    Many of the most remarkable tools in genome engineering have humble beginnings. This week, Broad core member Feng Zhang and his colleagues from MIT and Rockefeller University report on one of the newest additions to the growing list of genome editing technologies. Known as CRISPR (clustered regularly interspaced short palindromic repeats) systems,

    Read More
  • Five Questions for Mitch Guttman

    Haley Bridger, December 20th, 2012

    This week, Mitch Guttman — one of the Broad Institute’s first generation of “alumni” — was named to the Forbes "30 Under 30: Science and Healthcare" list of rising stars. This accolade comes on the heels of another prestigious honor for Guttman, who received an NIH Early Independence Award in the fall.

    Read More