Arrested development: head and neck cancer

Elizabeth Cooney, July 28th, 2011
  • Oral cancer squamous cell carcinoma
    Wikimedia Commons

Two teams – including one from the Broad Institute, Dana-Farber Cancer Institute, and the University of Pittsburgh School of Medicine – report surprising discoveries about head and neck cancer biology in back-to-back papers published in Science.

In the following video, Broad senior associate member Levi A. Garraway explains how genetic alterations appear to disrupt the normal development of cells in the mouth and throat, trapping them in an immature stage.  Check out video from his Pittsburgh colleague Jennifer R. Grandis here. To learn more, you can read the Broad press release here.