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Valeria Padovano


Gilder AL, Chapin HC, Padovano V, et al. Newly synthesized polycystin-1 takes different trafficking pathways to the apical and ciliary membranes. Traffic. 2018 Dec;19(12):933-945.

Padovano V, Kuo IY, Stavola LK, et al. The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function. Mol Biol Cell. 2017 Jan 15;28(2):261-269.

Valeria Padovano, Ph.D.

Valeria Padovano is a research scientist I in the Kidney Disease Initiative of the Broad Institute of MIT and Harvard, working under the direction of Anna Greka. The focus of her work is the study of mechanisms underlying the accumulation of intracellular toxic protein aggregates. Inherited mutations can prevent proteins from properly folding and as a result, the mutant proteins remain trapped in intracellular compartments, thus causing damage and cell death. In her research, Padovano investigates retention pathways shared among different diseases in order to find potential therapeutic targets.

Prior to joining the Broad Institute in April 2019, Padovano studied the molecular mechanisms of autosomal dominant polycystic kidney disease at Yale University, first as a postdoctoral associate and later as an associate research scientist. She had previously held a research fellowship in the Department of Pharmacology, Chemotherapy, and Toxicology at the University of Milan. During her time at Yale, she volunteered at New Haven Farms, a nonprofit promoting health and wellness through urban agriculture, and was a member of the Yale Postdoctoral Association’s Professional Development Committee.

Padovano holds a Ph.D. in pharmacology, a master’s degree in medical biotechnology and molecular medicine, and a bachelor’s degree in medical biotechnology, all earned from the University of Milan, Italy.

Contact Valeria Padovano via email at

January 2021