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Sumaiya Iqbal


Sumaiya Iqbal, Ph.D.

Sumaiya Iqbal is the group leader of the bioinformatics and computational biology group within the Center for the Development of Therapeutics (CDoT) at the Broad Institute of MIT and Harvard. She is a computer scientist by training but a life science researcher by determination; she uses data science and machine learning to bridge genetics, proteomics, and therapeutics. The focus of her group is twofold: develop AI-driven innovative technology for small-molecule hit identification using data from DNA-encoded library screening, HTS, etc., and drug target analysis by rationalizing functional consequences of genetic variants on protein structure and function.

Iqbal joined the Broad Institute in August 2017 as a postdoctoral associate while conducting her research at the Analytic and Translational Genetics Unit of Massachusetts General Hospital and Harvard Medical School. During her postdoctoral research in Mark Daly’s lab, she developed a statistical method for protein function-specific interpretation of genetic variants of 1,330 Mendelian disease genes. Following this work, she developed the Genomics to Proteins portal, a discovery tool for linking genetic screening outputs to protein sequence and structure for the full human proteome.

Iqbal earned her Ph.D. in computer science at the University of New Orleans, and her M.Sc. and B.Sc. in computer science from the Bangladesh University of Engineering and Technology

Contact Sumaiya Iqbal via email at

April 2022