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Stephen Fleming


Fleming SJ, Lu B, Golovchenko JA. Charge, diffusion, and current fluctuations of single-stranded DNA in an MspA nanopore. Biophys J. 2017;112(2):368–375.

Lu B, Fleming SJ, Szalay T, Golovchenko JA. Thermal motion of DNA in an MspA pore. Biophys J. 2015;109(7):1439–1445.

Stephen Fleming, Ph.D.

Stephen Fleming is a machine learning scientist I in the analytical method development group led by Mehrtash Babadi in the Data Sciences Platform of the Broad Institute of MIT and Harvard, which uses advanced machine learning techniques and probabilistic modeling to develop principled approaches to data analysis. Fleming works on developing data analysis methods for single-cell RNA sequencing data. His group is working to develop analysis methods that will be used by the Precision Cardiology Laboratory (part of the Broad–Bayer Collaboration) and the Human Cell Atlas project.

Fleming joined the Broad Institute in June 2018 after receiving his Ph.D. in physics from Harvard University. He also holds an M.Phil. in physics from the University of Cambridge, where he was a Churchill Scholar in the Physics of Medicine program, in addition to B.S. degrees in physics and biochemistry, both from Case Western Reserve University. As an undergraduate, he volunteered for the Case Western Engineers Without Borders program helping to design infrastructure for clean drinking water in Cameroon, Thailand, and the Dominican Republic.

Contact Stephen Fleming via email at

May 2021