Shao DD, Tsherniak A, Gopal S, et al. ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens. Genome Res. 2013;23:665-678.
Thompson J, Gopal S. Genetic algorithm learning as a robust approach to RNA editing site prediction. BMC Bioinformatics 2006;7:145. Correction in BMC Bioinformatics, 2006;7:406.
Shuba Gopal, Ph.D.
Shuba Gopal is a data scientist and People Insights program manager in Human Resources at the Broad Institute of MIT and Harvard. She is developing data-driven approaches to study how scientific collaborations work at Broad with the goal of enabling every scientific team to reach its true potential. Previously, she was a computational biologist in the Metabolomics Platform and in the Genetic Perturbation Platform at Broad. In both of those roles, Gopal analyzed data from high throughput methods including liquid chromatography tandem mass spectrometry (LC-MS) and large-scale shRNA screens to identify biomarkers and critical dependencies in a variety of disease states.
Gopal’s experience and capabilities include developing novel algorithms and statistical methods to identify biological signals predictive of disease states; integrating and visualizing multidimensional data to discern associations with clinically relevant outcomes; and leading complex projects involving multidisciplinary teams. She helped pioneer the first institute-wide integrated database comprising data from a wide variety of sources, including next generation sequencing, gene expression profiling, and cell-based assays. Her work was recognized with a Broad Excellence and Achievement award in 2014. In addition to her scientific contributions, Gopal was co-chair of an institute-wide strategic planning exercise known as Broadnext10. She helped lead a workstream focused on organizational dynamics and change management for the institute in the decade ahead.
Gopal earned her B.A. from Sarah Lawrence College and her Ph.D. in computational genomics from Rockefeller University. She taught bioinformatics at the Rochester Institute of Technology for five years prior to joining the Broad Institute in 2009.
You can contact Gopal via email at shuba [@] broadinstitute.org.