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Shan Lou


Dai H, Lou S, Zhang Y, et al. Transcriptional neural-like signaling contributes to an immune-suppressive tumor microenvironment. FASEB Bioadv. 2021;4(1):76-89. Published 2021 Oct 4. doi:10.1096/fba.2021-00076

Lou S, Adam Y, Weinstein EN, et al. Genetically targeted all-optical electrophysiology with a transgenic cre-dependent optopatch mouse. J Neurosci. 2016;36(43):11059-11073. doi:10.1523/JNEUROSCI.1582-16.2016

Lou S, Duan B, Vong L, Lowell BB, Ma Q.  et al. Runx1 Controls Terminal Morphology and Mechanosensitivity of VGLUT3-expressing C-Mechanoreceptors. J Neurosci. 2013;33(3):870-882. doi:10.1523/JNEUROSCI.3942-12.2013

Shan Lou, Ph.D.

Shan Lou is a senior scientist and translational lead in the vector engineering team in Stanley Center for Psychiatric Research. She currently works on in vitro pharmacokinetic and dynamic model/assay development with a focus on neurological disease gene therapies.

Lou has a decade of research experience in neuroscience, assay and tool development, drug discovery, and target identification. Prior to joining the Broad Institute in May 2021, she worked as the neuroscience lead in a flagship startup company, where she played a key role in building neural-oncology platforms. Prior to that, she worked on translating cutting-edge neurophysiological tools into bioelectronic therapeutics in the chemistry and chemical biology department of Harvard University. Lou was a recipient of a GSK bioelectronics innovation fellowship and a speaking award supported by the Dana-Farber Cancer Institute’s cancer biology department.

Lou holds a Ph.D. in neuroscience from Harvard University and Harvard Medical School and a B.A. in biology from Fudan University, Shanghai, China.

November 2022