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Scott Younger


Younger ST, Kenzelmann-Broz D, Jung H, et al. Integrative genomic analysis reveals widespread enhancer regulation by p53 in response to DNA damage. Nucleic Acids Res. 2015;43(9):4447–4462.

Younger ST, Corey DR. Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters. Nucleic Acids Res. 2011;39(13):5682–5691.

Janowski BA, Younger ST, Hardy DB, et al. Activating gene expression in mammalian cells with promoter-targeted duplex RNAs. Nat Chem Biol. 2007;3(3):166–173.

Scott Younger, Ph.D.

Scott Younger is a research scientist in the Genetic Perturbation Platform at the Broad Institute of MIT and Harvard working under the direction of David Root. For the past several years, he has been working with a variety of high-throughput sequencing-based screening technologies. In his current role, he consults and assists research groups interested in performing genome-scale genetic screens using CRISPR/Cas9. In addition, he is developing new methodologies that will further expand the utility of CRISPR-based approaches.

Younger joined the Broad Institute in his current post in 2016 after having completed his postdoctoral studies jointly at Harvard University and the Broad Institute as an American Cancer Society Fellow. He holds a Ph.D. in cell and molecular biology from the University of Texas Southwestern Medical Center. He also received an M.S. in biotechnology from the University of Texas at San Antonio and a B.S.I. in bioinformatics from Baylor University.

Contact Scott Younger at

December 2016