Pierre Jean-Beltran, Ph.D.
Pierre Jean-Beltran is a postdoctoral fellow in the Proteomics Platform at the Broad Institute of MIT and Harvard working under the direction of Steve Carr. Jean-Beltran’s work focuses on the study of the molecular response and adaptation to physical activity using animal models and human participants, as part of the NIH-funded Molecular Transducers of Physical Activity Consortium. Jean-Beltran applies mass spectrometry technologies for the global quantification of protein abundance, phosphorylation, acetylation, and ubiquitylation status in animal and human tissues. He also develops and uses computational approaches to integrate these proteomic datasets with transcriptomic, metabolomic, and chromatin accessibility datasets, to extract multi-omic signatures associated with exercise.
In addition, Jean-Beltran is interested in the understanding of the spatial organization of the proteome and is involved in studies seeking to map proteins involved in inter-organ communication using proximity labeling proteomic technologies.
Pierre holds a Ph.D. in molecular biology from Princeton University. His thesis work under the Cristea Lab focused on the integration of proteomic, computational, and microscopy techniques to study host-pathogen interactions and the spatiotemporal regulation of organelle proteomes in the context of productive viral infection.