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Nikhil Wagle

Nikhil Wagle, M.D.

Nikhil Wagle is an assistant professor of medicine at Harvard Medical School, a medical oncologist at Dana-Farber Cancer Institute, and an associate member of the Broad Institute of MIT and Harvard. He is the deputy director of the Center for Cancer Precision Medicine at Dana-Farber Cancer Institute.

Wagle leads a translational research program in breast cancer and precision cancer medicine. The major goals of his work are to better understand the biology of metastatic breast cancer and to develop new ways to overcome or prevent drug resistance in patients with advanced breast cancer. Ultimately, his research aims to identify characteristics of tumors that might improve clinical decision-making for patients with advanced cancer.

He also directs Count Me In, which launches patient-driven research projects across multiple cancer types. The program’s first project, The Metastatic Breast Cancer Project (mbcproject.org), is a nationwide patient-driven research initiative that engages patients with advanced breast cancer through social media and seeks to empower them to accelerate cancer research through sharing their samples and clinical information. The project’s outreach program, developed in collaboration with advocacy organizations and patients, serves to connect thousands of patients around the U.S. with metastatic breast cancer research, allowing them to participate regardless of where they live. Additional projects for patients with angiosarcoma and metastatic prostate cancer have been launched, with several more in development.

Wagle has received grant funding from Susan G. Komen, the Breast Cancer Research Foundation, the V Foundation, the Breast Cancer Research Alliance, and the Department of Defense. He is a recipient of several awards and honors, including a Young Investigator Award from the Conquer Cancer Foundation of the American Society of Clinical Oncology, the 2013 Landon Foundation-AACR INNOVATOR Award for Research in Personalized Cancer Medicine, and the inaugural 2016 AACR NextGen Award for Transformative Cancer Research. His work has been published in the New England Journal of Medicine, the Journal of Clinical Oncology, Cancer Discovery, and Nature Medicine. 

Wagle is also co-founder of Doctors for America, a grassroots organization of over 18,000 doctors and medical students in the United States who are working to build a better health care system for all Americans.  

Wagle received his M.D. from Harvard Medical School and completed his residency training in internal medicine at Brigham and Women’s Hospital, where he also served as chief medical resident; he completed his fellowship training in hematology/oncology in the Dana-Farber/Partners program.

May 2018