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Liz Gaskell


Kim IS, Wu J, Rahme GJ, Battaglia S, Dixit A, Gaskell E, Chen H, Pinello L, Bernstein BE. Parallel single-cell RNA-seq and genetic recording reveals lineage decisions in developing embryoid bodies. Cell Rep. 2020 Oct 6;33(1):108222. 

Cejas P ... Gaskell E ... Bernstein BE, Shivdasani RA. Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors. Nature Medicine. 2019 25: 1260–1265.

Flavahan WA, Gaskell E, Bernstein BE. Epigenetic plasticity and the hallmarks of cancer. Science. 2017 Jul 21;357(6348).

Gaskell E. From mechanism to observation and back again. Mol Cell. 2016;62(5):649.

Liz Gaskell, Ph.D.

Liz Gaskell is associate director of the Gene Regulation Observatory (GRO). She also plays a leading role in the Epigenomics Program at the Broad Institute of MIT and Harvard.

The GRO launched in 2020, and brings together a community to investigate the regulation of context-specific gene expression within cells, from transcription factors, chromatin, and nuclear architecture to the functional elements, regulatory interactions, and circuits that control cell states and transitions. The GRO drives progress by initiating and coordinating flagship projects; nucleating communities across scientific disciplines; working with the Cell Circuits and Epigenomics Programs; pioneering the creation of powerful new tools; and ensuring that robust single-cell capabilities are available to the Broad community.

Gaskell leads the scientific strategy and operations for the GRO. She works with the GRO’s director, Brad Bernstein, to chart the long-term scientific course of the observatory. Her team leads the GRO’s community-building and outreach activities, including organizing the joint CC&E weekly seminar series, and assists GRO investigators in planning, organization, and execution of projects.

Prior to joining the Broad Institute in July of 2016, Gaskell worked in scientific publishing, first as an editor for Genome Biology and then for Molecular Cell, where she specialized in genome regulation, chromatin biology, systems biology, and DNA and RNA metabolism. She also engaged in outreach work to make the process of scientific publishing more transparent, particularly for trainees and new PIs. She therefore has extensive experience in life science publishing from both the subscription and open-access models. She also has run several successful international scientific meetings on topics from ubiquitin signaling to gender in science.

Gaskell holds a Ph.D. in biochemistry from the University of Leeds and a B.Sc. (Hons) in biochemistry with applied molecular biology from the University of Manchester.

Contact Liz Gaskell at

January 2021