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Jon Goldstein

Publications

Hua Z, Huang X, Bregman H, et al. 2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1γ) inhibitors. Bioorg Medicinal Chem Lett. 2012;22(17):5392–5395.

Huang H, Acquaviva L, Berry V,  et al. Structure-based design of potent and selective CK1γ inhibitors. ACS Med Chem Lett. 2012;3(12):1059–1064.

Goldstein JT, Dobrzyn A, Clagett-Dame M, et al. Isolation and characterization of unsaturated fatty acids as natural ligands for the retinoid-X receptor. Arch Biochem Biophys. 2003;420(1):185–193.

Jon Goldstein, Ph.D.

Jon Goldstein works as a research scientist II in the Cancer Program of the Broad Institute of MIT and Harvard as a member of the Meyerson Lab under the direction of Craig Strathdee. His research focuses on harnessing discoveries from large-scale sequencing of cancer genomes to identify and validate new candidate therapeutic drug targets and to translate these findings into genomically targeted drug discovery programs.

Prior to joining the Broad Institute in June 2014, Goldstein worked in the pharmaceutical industry as a senior scientist for various companies. During his tenure with Amgen, he worked on metabolic disorders and oncology therapeutic investigations; this was followed by a stint working on therapeutic antibody drug discovery at Abbott Laboratories/AbbVie. Goldstein is a member of the American Association for Cancer Research.

Goldstein holds a Ph.D. in Biochemistry from University of Wisconsin, Madison and a B.Sc. in chemistry from Western University (London, Ontario, Canada).

June 2016