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Jiangchuan Ye


Ye J, Tucker NR, Weng LC, et al. A Functional Variant Associated with Atrial Fibrillation Regulates PITX2c Expression through TFAP2a. Am J Hum Genet. 2016 Dec 1;99(6):1281-1291.

Tucker NR, Mahida S, Ye J, et al. Gain-of-function mutations in GATA6 lead to atrial fibrillation. Heart Rhythm. 2017 Feb;14(2):284-291. Epub 2016 Oct 15.

Tucker NR, Dolmatova EV, Lin H, Cooper RR, Ye J, et al. Diminished PRRX1 Expression Is Associated With Increased Risk of Atrial Fibrillation and Shortening of the Cardiac Action Potential. Circ Cardiovasc Genet. 2017 Oct;10(5). pii: e001902.

Jiangchuan Ye, M.D., Ph.D.

Jiangchuan Ye is a research scientist working under the direction of Patrick Ellinor in the Cardiovascular Disease Initiative (CVDi), part of the Broad–Bayer Collaboration in Cardiovascular Disease at the Broad Institute of MIT and Harvard. Within the program, Ye’s research investigates molecular and cellular mechanisms underlying the genetic underpinnings of atrial fibrillation. Another research focus is establishing high-throughput phenotypic screens using pluripotent stem cells and genome editing techniques to explore potential drug targets.

Ye joined the Broad Institute in November 2017 after his five-year research fellowship at Massachusetts General Hospital and Harvard Medical School, where he investigated functional genomics of arrhythmias, particularly atrial fibrillation. He had previously completed his M.D./Ph.D. program in cardiovascular medicine at Tongji University, China, where he was the recipient of the National Inspirational Scholarship and Scholarship for Outstanding Students of Tongji University.

Contact Jiangchuan Ye via email at

February 2019