Kong X, Yao T, Zhou P, Kazak L, Tenen D, Lyubetskaya A, Dawes BA, Tsai L, Kahn BB, Spiegelman BM, Liu T, and Rosen ED. Brown adipose tissue controls skeletal muscle function via the secretion of myostatin. Cell Metabolism, 2018, 28:631-643.
Roh HC, Tsai, LT-Y, Shao M, Tenen D, Shen Y, Kumari M, Lyubetskaya A, Jacobs C, Dawes B, Gupta RK, and Rosen ED. Warming induces significant reprogramming of beige, but not brown, adipocyte cellular identity. Cell Metabolism, 2018, 27:1121-1137.
Evan Rosen, Ph.D.
Evan Rosen is an institute member of the Broad Institute of MIT and Harvard, a principal investigator at Beth Israel Deaconess Medical Center, and a professor at Harvard Medical School.
Rosen specializes in understanding the transcriptional pathways that underlie metabolic diseases like obesity and Type 2 diabetes. In particular, he has a longstanding interest in using genomic and epigenomic approaches to identify novel transcription factors and pathways that regulate processes such as adipogenesis, lipid handling, insulin resistance, and metabolic memory. His ultimate goal is to define novel targets that can be manipulated to improve outcomes in metabolic disease.
Rosen received his B.S. from Cornell University. He received his M.D. and Ph.D. from the University of Michigan. He completed his residency in Internal Medicine at Brigham and Women’s Hospital and a Fellowship in Endocrinology at Massachusetts General Hospital. He received his post-doctoral training in the lab of Bruce Spiegelman at the Dana-Farber Cancer Institute.