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Diane P. Genereux


Choi M, Genereux DP, Goodson J, et al. Epigenetic memory via concordant DNA methylation is inversely correlated to developmental potential of mammalian cells. PLoS Genet. 2017;13(11):e1007060. 

Genereux DP, Laird CD. At what rate do new premutation alleles arise at the fragile X locus? Hum Genet. 2013 Jun;132(6):715-717. 

Genereux DP. Asymmetric strand segregation: epigenetic costs of genetic fidelity? PLoS Genet. 2009 Jun;5(6):e1000509.

Diane P. Genereux, Ph.D.

Diane P. Genereux is a research scientist II in the Vertebrate Genome Biology Group at the Broad Institute of MIT and Harvard, where she works under the direction of Elinor Karlsson. Genereux's work in epigenetics focuses on developing molecular and statistical methods to track the fidelity of epigenetic information through cellular differentiation. At Broad, she is using comparative genomics and epigenomics to investigate how cells from species with flexible homeostasis endure variation in blood glucose and oxygen, and body temperature. She is also a co-chair of the Program in Medical and Population Genetics’s Primer series.

Genereux completed a postdoctoral fellowship at the University of Washington and was previously assistant professor of biology at Westfield State University. She assumed her current post at the Broad Institute in 2016. 

Genereux holds a Ph.D. in mathematical biology from Emory University.

Contact Diane P. Genereux via email at

February 2021