Bo Xia

Bo Xia, Ph.D.

Bo Xia

Bo Xia is a fellow in the Gene Regulation Observatory (GRO) and a principal investigator at the Broad Institute of MIT and Harvard. He is also a junior fellow of the Society of Fellows at Harvard University. Xia aims to understand the principles and mechanisms of genome organization, how their dynamic regulation determines cell fates, and more importantly, how they modulate human development and go awry in diseases.

Xia started his career as an independent research associate in Chengqi Yi’s lab at Peking University, where he led the development of chemical technologies for epigenomic analyses. Xia received his Ph.D. from NYU School of Medicine in 2022, co-mentored by Itai Yanai and Jef D. Boeke. During his graduate studies, Xia pioneered a few innovative studies on genome regulation and its impact on human development and evolution, including revealing the genetic basis of tail-loss evolution in humans and apes. 

Xia joined the GRO at the Broad Institute in 2022. Xia will lead a team to develop high-throughput experimental and computational approaches to systematically identify functional DNA elements and novel regulators of 3D genome organization. Xia’s team integrates multidisciplinary techniques across genomics and computational biology, molecular biology, and synthetic and chemical biology to investigate the principles and mechanisms of 3D genome regulation. 

Xia is a recipient of multiple prestigious early career-stage awards, including the 2020 Regeneron Prize for Creative Innovation, the Harold M. Weintraub Graduate Student Award, and the NIH Director’s Early Independence Award.

Contact Bo Xia via email at xiabo {at}


October 2022