Mead, BE*, Hattori, K*, Levy, L. et al. Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation. Nat Biomed Eng. 2022;6(4):476-494. doi:10.1038/s41551-022-00863-9
Mead BE*, Ordovas-Montanes J*, Braun AP, et al. Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. BMC Biol. 2018;16(1):62. Published 2018 Jun 5. doi:10.1186/s12915-018-0527-2
Yin X, Mead BE, Safaee H, Langer R, Karp JM, Levy O. Engineering Stem Cell Organoids. Cell Stem Cell. 2016;18(1):25-38. doi:10.1016/j.stem.2015.12.005
Ben Mead, Ph.D.
Ben Mead is a research scientist in the lab of institute member Alex Shalek and the Klarman Cell Observatory of the Broad Institute of MIT and Harvard. He works on applying single-cell genomics to improve cellular models of human disease and identify new drug targets and therapeutics. Mead’s research seeks to utilize complex cellular models including organoids in scalable, high-content screening experiments to enable functional discoveries of key mediators of tissue biology.
Prior to joining the Broad Institute in 2021, Mead was a MIT-GSK G.B. Elion postdoctoral fellow and completed his Ph.D. as an NSF graduate fellow in the groups of Jeff Karp and Robert Langer through the Harvard-MIT Health Sciences & Technology Program. He holds a bachelor’s degree in chemical and biological engineering from the University of Colorado Boulder. In addition to academic pursuits, Mead was an intern at Flagship Pioneering and has consulted for multiple Langer-founded and Flagship startups.