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Ashlee Earl


Cohen KA, Abeel T, Manson McGuire A, et al. Evolution of extensively drug-resistant tuberculosis over four decades: Whole genome sequencing and dating analysis of Mycobacterium tuberculosis isolates from KwaZulu-Natal. PLoS Med. 2015 Sep 29;12(9):e1001880.

Lebreton F, van Schaik W, McGuire AM, et al. Emergence of epidemic multidrug-resistant Enterococcus faecium from animal and commensal strains. MBio. 2013 Aug 20;4(4): e00534-13.

Human Microbiome Project Consortium. Structure, function and diversity of the healthy human microbiome. Nature. 2012 Jun 13;486(7402):207-14.

Ashlee Earl, Ph.D.

Ashlee M. Earl is a research scientist and group leader for the Bacterial Genomics Group at the Broad Institute of MIT and Harvard. Within the Broad Institute’s Genomic Center for Infectious Diseases, Earl is working to understand the relationship between microbes and human health including how multi-drug resistant pathogens emerge and spread.

Earl coordinated much of the Broad’s research in the Human Microbiome Project and now leads a team of computational biologists to develop and utilize an array of ‘omics analytical approaches to dissect bacterial and host contributions to several infectious diseases. She has organized and led dozens of local and international collaborations to bring genomic approaches to the study of tuberculosis, urinary tract infections, and hospital-acquired infections caused by the enterococci and carbapenem-resistant Enterobacteriaceae.

Prior to joining the Broad Institute in 2009, Earl received her B.S. and Ph.D. in microbiology from Louisiana State University and postdoctoral training from Harvard Medical School with Dr. Roberto Kolter. In addition to expertise in microbiology, microbial genomics, genetics, metagenomics, and human microbiome research, Earl has experience in grant writing, scientific communication, teaching, and mentoring.

Contact Ashlee Earl via email at

January 2016