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Abigail Manson


Manson AL, Cohen KA, Abeel T, et al. Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance. Nat Genet. 2017 Jan 16.

Manson McGuire A, Cochrane K, Griggs A, et al. Evolution of invasion in a diverse set of Fusobacterium. mBio. 2014;5(6):e01864-14.

Lebreton F, van Schaik W, Manson McGuire A, et al. Emergence of epidemic multi-drug resistant Enterococcus faecium from animal and commensal strains. mBio. 2013; 4(4): e00534-13.

Abigail Manson, Ph.D.

Abigail Manson (formerly Manson McGuire) is a senior computational biologist I in the Genome Sequencing and Analysis Program at the Broad Institute of MIT and Harvard. She conducts comparative analysis of whole genome sequences, with a focus on understanding the evolution of virulence and antibiotic resistance. She has worked on a wide variety of bacteria, including Mycobacterium tuberculosis, Enterococcus, Fusobacterium, and E. coli, with particular emphasis on the evolution of drug resistance and virulence factors.

A computational biologist, Manson previously completed a comparative analysis of tuberculosis genomes. Before that, she studied alternative splicing of genetic material and worked on predicting noncoding RNAs — RNA molecules that are not translated into proteins — in the fungus Aspergillus.

Manson joined the Broad as postdoc after receiving bachelor’s degrees in physics and mathematics at Washington University and a Ph.D. in biophysics at Harvard University.

Contact Abigail Manson via email at

February 2017