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How Genome-Wide Association Studies Transform Care for Patients at Risk of Glaucoma.
Zebardast N, Wiggs JL. How Genome-Wide Association Studies Transform Care for Patients at Risk of Glaucoma. Expert review of ophthalmology. 2024;19(4):243-246. doi:10.1080/17469899.2024.2365736DOIGoogle ScholarPubMed
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Descriptives and genetic correlates of eating disorder diagnostic transitions and presumed remission in the Danish registry.
Abdulkadir M, Larsen JT, Clausen L, et al. Descriptives and genetic correlates of eating disorder diagnostic transitions and presumed remission in the Danish registry. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.09.05.24313142DOIGoogle ScholarPubMed
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Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial.
Zou RS, Ruan Y, Truong B, et al. Polygenic Scores and Preclinical Cardiovascular Disease in Individuals With HIV: Insights From the REPRIEVE Trial. Journal of the American Heart Association. 2024:e033413. doi:10.1161/JAHA.123.033413DOIGoogle ScholarPubMed
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Polygenic burden and its association with baseline cognitive function and postoperative cognitive outcome in temporal lobe epilepsy.
Arrotta K, Ferguson L, Thompson N, et al. Polygenic burden and its association with baseline cognitive function and postoperative cognitive outcome in temporal lobe epilepsy. Epilepsy & behavior : E&B. 2024;153:109692. doi:10.1016/j.yebeh.2024.109692DOIGoogle ScholarPubMed
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[Genetic basis of atrial fibrillation-on the road to precision medicine].
Kany S, Schnabel RB. [Genetic basis of atrial fibrillation-on the road to precision medicine]. Herzschrittmachertherapie & Elektrophysiologie. 2023. doi:10.1007/s00399-023-00974-zDOIGoogle ScholarPubMed
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Youth Team Sports Participation Associates With Reduced Dimensional Psychopathology Through Interaction With Biological Risk Factors.
Kunitoki K, Hughes D, Elyounssi S, et al. Youth Team Sports Participation Associates With Reduced Dimensional Psychopathology Through Interaction With Biological Risk Factors. Biological psychiatry global open science. 2023;3(4):875-883. doi:10.1016/j.bpsgos.2023.02.001DOIGoogle ScholarPubMed
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Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins.
Drouard G, Hagenbeek FA, Whipp AM, et al. Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins. BMC medicine. 2023;21(1):508. doi:10.1186/s12916-023-03198-7DOIGoogle ScholarPubMed
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Interplay between polygenic risk for mood disorders and stressful life events in bipolar disorder.
Hosang GM, Shakoor S, King N, et al. Interplay between polygenic risk for mood disorders and stressful life events in bipolar disorder. Journal of affective disorders. 2024. doi:10.1016/j.jad.2024.01.167DOIGoogle ScholarPubMed
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Improving Polygenic Risk Scores for Coronary Artery Disease: What Helps and by How Much?
Ajufo EC, Aragam KG. Improving Polygenic Risk Scores for Coronary Artery Disease: What Helps and by How Much?. JACC. Basic to translational science. 2023;8(12):1500-1502. doi:10.1016/j.jacbts.2023.10.005DOIGoogle ScholarPubMed
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Integration of Biomarker Polygenic Risk Score Improves Prediction of Coronary Heart Disease.
Lin J, Mars N, Fu Y, et al. Integration of Biomarker Polygenic Risk Score Improves Prediction of Coronary Heart Disease. JACC. Basic to translational science. 2023;8(12):1489-1499. doi:10.1016/j.jacbts.2023.07.006DOIGoogle ScholarPubMed
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In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Broad Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

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Through Broad's Scientists in the Classroom program, Broad researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

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In November 2022, Broad’s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Broad’s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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