Serine Endopeptidases | Broad Institute

CylA is a sequence-specific protease involved in toxin biosynthesis.

Tang W, Bobeica SC, Wang L, van der Donk WA. CylA is a sequence-specific protease involved in toxin biosynthesis. J Ind Microbiol Biotechnol. 2019;46(3-4):537-549. doi:10.1007/s10295-018-2110-9PubMed Google Scholar DOI

Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses.

Wang M, Lee-Kim VS, Atri DS, et al. Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights From Functional Genomics and Large-Scale Sequencing Analyses. Circ Genom Precis Med. 2021;14(5):e003399. doi:10.1161/CIRCGEN.121.003399PubMed Google Scholar DOI

The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression.

Lammert DB, Middleton FA, Pan J, Olson EC, Howell BW. The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression. J Neurochem. 2017;142(1):89-102. doi:10.1111/jnc.14045PubMed Google Scholar DOI

Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.

C Y Ng M, Graff M, Lu Y, et al. Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium. PLoS Genet. 2017;13(4):e1006719. doi:10.1371/journal.pgen.1006719PubMed Google Scholar DOI

Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture.

Paik EJ, O’Neil AL, Ng SY, Sun C, Rubin LL. Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture. Sci Rep. 2018;8(1):804. doi:10.1038/s41598-018-19291-4PubMed Google Scholar DOI

Site-specific identification and quantitation of endogenous SUMO modifications under native conditions.

Lumpkin RJ, Gu H, Zhu Y, et al. Site-specific identification and quantitation of endogenous SUMO modifications under native conditions. Nat Commun. 2017;8(1):1171. doi:10.1038/s41467-017-01271-3PubMed Google Scholar DOI

Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.

Sandoval GJ, Pulice JL, Pakula H, et al. Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis. Mol Cell. 2018;71(4):554-566.e7. doi:10.1016/j.molcel.2018.06.040PubMed Google Scholar DOI

Development of a novel, sensitive cell-based corin assay.

Lambertz P, Theisen L, Längst N, et al. Development of a novel, sensitive cell-based corin assay. Biochem Pharmacol. 2019;160:62-70. doi:10.1016/j.bcp.2018.12.009PubMed Google Scholar DOI

Layer I Interneurons Sharpen Sensory Maps during Neonatal Development.

Che A, Babij R, Iannone AF, et al. Layer I Interneurons Sharpen Sensory Maps during Neonatal Development. Neuron. 2018;99(1):98-116.e7. doi:10.1016/j.neuron.2018.06.002PubMed Google Scholar DOI

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics.

Muus C, Luecken MD, Eraslan G, et al. Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nat Med. 2021;27(3):546-559. doi:10.1038/s41591-020-01227-zPubMed Google Scholar DOI