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A field resource for the glioma cerebrospinal fluid proteome: impacts of resection and location on biomarker discovery.
Riviere-Cazaux C, Graser CJ, Warrington AE, et al. A field resource for the glioma cerebrospinal fluid proteome: impacts of resection and location on biomarker discovery. Neuro-oncology. 2024. doi:10.1093/neuonc/noae277DOIGoogle ScholarPubMed
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The BNT162b2 mRNA vaccine demonstrates reduced age-associated T1 support and .
Brook B, Checkervarty AK, Barman S, et al. The BNT162b2 mRNA vaccine demonstrates reduced age-associated T1 support and . iScience. 2024;27(11):111055. doi:10.1016/j.isci.2024.111055DOIGoogle ScholarPubMed
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The BNT162b2 mRNA vaccine demonstrates reduced age-associated T1 support and .
Brook B, Checkervarty AK, Barman S, et al. The BNT162b2 mRNA vaccine demonstrates reduced age-associated T1 support and . iScience. 2024;27(11):111055. doi:10.1016/j.isci.2024.111055DOIGoogle ScholarPubMed
Read more
Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes.
Ogasawara D, Konrad DB, Tan ZY, et al. Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes. Cell chemical biology. 2024. doi:10.1016/j.chembiol.2024.10.005DOIGoogle ScholarPubMed
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Proteogenomic analysis integrated with electronic health records data reveals disease-associated variants in Black Americans.
Tahir UA, Barber JL, Cruz DE, et al. Proteogenomic analysis integrated with electronic health records data reveals disease-associated variants in Black Americans. The Journal of clinical investigation. 2024;134(21). doi:10.1172/JCI181802DOIGoogle ScholarPubMed
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Hypometric genetics: Improved power in genetic discovery by incorporating quality control flags.
Tanigawa Y, Kellis M. Hypometric genetics: Improved power in genetic discovery by incorporating quality control flags. American journal of human genetics. 2024. doi:10.1016/j.ajhg.2024.09.008DOIGoogle ScholarPubMed
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Proteomic Profile of the p.K56M HFpEF Risk Variant.
Giro P, Filipp M, Zhang MJ, et al. Proteomic Profile of the p.K56M HFpEF Risk Variant. JACC. Basic to translational science. 2024;9(9):1073-1084. doi:10.1016/j.jacbts.2024.05.016DOIGoogle ScholarPubMed
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Proteomic Profile of the p.K56M HFpEF Risk Variant.
Giro P, Filipp M, Zhang MJ, et al. Proteomic Profile of the p.K56M HFpEF Risk Variant. JACC. Basic to translational science. 2024;9(9):1073-1084. doi:10.1016/j.jacbts.2024.05.016DOIGoogle ScholarPubMed
Read more
Hypometric genetics: Improved power in genetic discovery by incorporating quality control flags.
Tanigawa Y, Kellis M. Hypometric genetics: Improved power in genetic discovery by incorporating quality control flags. American journal of human genetics. 2024. doi:10.1016/j.ajhg.2024.09.008DOIGoogle ScholarPubMed
Read more
Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics.
Baek K, Metivier RJ, Burman SSR, et al. Unveiling the hidden interactome of CRBN molecular glues with chemoproteomics. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.11.612438DOIGoogle ScholarPubMed
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In March of 2020, Broad Institute converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Broad Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity.

Through Broad's Scientists in the Classroom program, Broad researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

Every summer, 18 high school students spend six weeks at Broad working side-by-side with mentors on cutting-edge research.

In November 2022, Broad’s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Broad’s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Broad Institute has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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