Polymerase Chain Reaction | Broad Institute

A case of mistaken identity.

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Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis.

Crews CM, Lane WS, Schreiber SL. Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis. Proc Natl Acad Sci U S A. 1996;93(9):4316-9.Google Scholar PubMed

Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens.

Hegde M, Strand C, Hanna RE, Doench JG. Uncoupling of sgRNAs from their associated barcodes during PCR amplification of combinatorial CRISPR screens. PLoS One. 2018;13(5):e0197547. doi:10.1371/journal.pone.0197547PubMed DOI Google Scholar

Cloning, Zn2+ binding, and structural characterization of the guanine nucleotide exchange factor human Mss4.

Yu H, Schreiber SL. Cloning, Zn2+ binding, and structural characterization of the guanine nucleotide exchange factor human Mss4. Biochemistry. 1995;34(28):9103-10.Google Scholar PubMed

Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association.

Renneville A, Boissel N, Nibourel O, et al. Prognostic significance of DNA methyltransferase 3A mutations in cytogenetically normal acute myeloid leukemia: a study by the Acute Leukemia French Association. Leukemia. 2012;26(6):1247-54. doi:10.1038/leu.2011.382PubMed DOI Google Scholar

Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70.

Graef IA, Holsinger LJ, Diver S, Schreiber SL, Crabtree GR. Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70. EMBO J. 1997;16(18):5618-28. doi:10.1093/emboj/16.18.5618PubMed DOI Google Scholar

An Integrative Transcriptomic and Metabolomic Study of Lung Function in Children With Asthma.

Kelly RS, Chawes BL, Blighe K, et al. An Integrative Transcriptomic and Metabolomic Study of Lung Function in Children With Asthma. Chest. 2018;154(2):335-348. doi:10.1016/j.chest.2018.05.038Google Scholar PubMed DOI

Overproduction of proteins using expression-cassette polymerase chain reaction.

MacFerrin KD, Chen L, Terranova MP, Schreiber SL, Verdine GL. Overproduction of proteins using expression-cassette polymerase chain reaction. Methods Enzymol. 1993;217:79-102.PubMed Google Scholar

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

Jin YJ, Albers MW, Lane WS, Bierer BE, Schreiber SL, Burakoff SJ. Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13. Proc Natl Acad Sci U S A. 1991;88(15):6677-81.PubMed Google Scholar

Overproduction and dissection of proteins by the expression-cassette polymerase chain reaction.

MacFerrin KD, Terranova MP, Schreiber SL, Verdine GL. Overproduction and dissection of proteins by the expression-cassette polymerase chain reaction. Proc Natl Acad Sci U S A. 1990;87(5):1937-41.PubMed Google Scholar